Thereafter, helen hobbs and jonathan cohen found that individuals with loss of function in pcsk9 identified in the dallas heart study seemed to enjoy protection from atherosclerotic cardiovascular. Pcsk9 = proprotein convertase subtilisin/kexin type 9 Apo (b) = apolipoprotein (b)
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Hefh = heterozygous familial hypercholesterolemia
Hofh = homozygous familial hypercholesterolemia
