At the cellular level, bifidobacterium upregulates suppressive regulatory t cells, maintains intestinal barrier function, modulates dendritic cell and macrophage activity, and dampens intestinal th2 and th17 programs. Screening of a large collection of gut symbionts on gf mice identified a b A lack of bifidobacteria and/or their genes required for the utilization of human milk oligosaccharides from breast milk is associated with systemic inflammation and immune imbalance early in life
Kaitlyn Gill - 54 Below
The early life period is a critical phase for the colonization of initial gut microbes in infants, during which the immune system develops and matures…