The overexpression of both is closely related to the development and metastasis of tumors Similarly to alk nsclc, patients with ros1+ nsclc tend to have minimal smoking history and be of the female sex. Although their frequency is relatively low, their detection is important for patient care and guides therapeutic decisions
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The accepted methods used for th …
Introduction anaplastic lymphoma kinase (alk) is a tyrosine kinase that can be aberrantly expressed in several tumor types
The most common alk rearrangement in nsclc juxtaposes the 5' end of the echinoderm microtubule.
