Stat6 positive (pathol res pract 2018;214:1544) Pash (pseudoangiomatous stromal hyperplasia) is specific to breast int ra lobular surrounds acini in tdlus compared to interlobular stroma, looser in appearance or even myxoid often small numbers of inflammatory cells lesions arising here are biphasic involving epithelial and stromal components, including fibroadenoma, phyllodes tumor Hamartoma is a well circumscribed, often encapsulated mass composed of normal but disorganized components of breast tissue
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Columnar cell lesions of breast are enlarged terminal duct lobular units (tdlus) with irregularly dilated acini lined by columnar epithelial cells